Immunology

(Products approved for use in Canada)

Drug Class

Generic Name

Trade Name

Active Immunizing Agents

Bacterial Vaccines, single entity

Bacillus Calmette-Guerin (BCG) vaccine (live attenuated)

BCG Vaccine

cholera vaccine (oral, live, attenuated)

Mutacol

Haemophilus influenzae Type b conjugate vaccine

Act-HIB, PedvaxHIB

meningococcal conjugate vaccine

Meningitec, Menjugate, NeisVac-C

meningococcal polysaccharide vaccine

Mencevax AC, Menomune

pneumococcal conjugate vaccine

Prevnar

pneumococcal polysaccharide vaccine

Pneumo 23, Pneumovax 23

travellers’ diarrhea and cholera vaccine (oral, inactivated)

Dukoral

typhoid (Salmonella typhi Vi capsular polysaccharide) vaccine

Typherix, Typhim Vi

typhoid (Salmonella typhi Ty21a) vaccine (oral, live, attenuated)

Vivotif Berna, Vivotif Berna L

Bacterial Toxoids

diphtheria and tetanus toxoids

Td Adsorbed

tetanus toxoid

Viral Vaccines

Viral Vaccines, single entity

hepatitis A vaccine (inactivated)

Avaxim, Epaxal, Havrix, Vaqta

hepatitis B vaccine (recombinant)

Engerix-B, Recombivax HB

combined hepatitis A and hepatitis B vaccine

Twinrix

influenza virus vaccine (inactivated, split-virus)

Fluviral S/F, Fluzone, Vaxigrip

Japanese encephalitis virus vaccine (inactivated)

JE-VAX

poliomyelitis vaccine (IPV) (inactivated)

rabies vaccine (inactivated)

IMOVAX Rabies

Drug Class

Generic Name

Trade Name

Viral Vaccines cont’d

Viral Vaccines, single entity cont’d

varicella virus vaccine (live, attenuated)

Varilrix, Varivax III

yellow fever vaccine (live, attenuated)

YF-VAX

Viral Vaccines, combination

measles and rubella virus vaccine (live, attenuated)

MoRu-Viraten

measles, mumps, rubella virus vaccine (live, attenuated) — MMR

M-M-R II, Priorix

Viral and Bacterial Vaccines with Toxoids

pertussis vaccine with diphtheria and tetanus toxoids

Adacel, Tripacel

poliomyelitis vaccine with diphtheria and tetanus toxoids

DT-Polio adsorbed (< 7 yrs), Td-Polio Adsorbed (≥ 7 years and Adults)

pertussis and poliomyelitis vaccines with diphtheria and tetanus toxoids

Quadracel

Haemophilus influenzae type b conjugate and pertussis and poliomyelitis vaccines with diphtheria and tetanus toxoids

Pentacel

Passive Immunizing Agents

Immune Globulin, standard (non-specific, human, pooled)

immune globulin IM

BAYGAM

immune globulin IV

Gamimune N, Gammagard S/D, Gamunex, Iveegam Immuno

Immune Globulin, specific (human, pooled)

cytomegalovirus immune globulin

Cytogam

hepatitis B immune globulin

BAYHEP B

rabies immune globulin

BAYRAB, Imogam Rabies

Rho (D) immune globulin

WinRho SDF

tetanus immune globulin

BAYTET

varicella zoster immune globulin

Monoclonal Antibody for Passive Immunization

palivizumab

Synagis

Drug Class

Generic Name

Trade Name

Passive Immunizing Agents

Antitoxins and Antivenins (equine or ovine)

botulism antitoxin (equine)

diphtheria antitoxin (equine)

snake antivenin (ovine)

CroFab (Crotalidae Polyvalent Immune Fab)

spider (black widow) antivenin (equine)

Antivenin Lyovac

Immunosuppressants

Corticosteroids, Systemic

betamethasone

Betnesol, Celestone

cortisone acetate

dexamethasone

Dexasone

hydrocortisone

Cortef

hydrocortisone sodium succinate

Solu-Cortef

methylprednisolone

Medrol

methylprednisolone acetate

Depo-Medrol

methylprednisolone sodium succinate

Solu-Medrol

prednisolone

Pediapred

prednisone

Winpred

triamcinolone

triamcinolone acetonide

Kenalog

Antimetabolites

azathioprine

Imuran

mercaptopurine

Purinethol

methotrexate

mycophenolate mofetil

Cellcept

mycophenolate sodium

Myfortic

Calcineurin Inhibitors

cyclosporine

Neoral, Sandimmune IV

pimecrolimus

Elidel

tacrolimus

Prograf, Protopic

Miscellaneous

cyclophosphamide

Cytoxan, Procytox

sirolimus

Rapamune

Drug Class

Generic Name

Trade Name

Immunosuppressants cont’d

Monoclonal Antibodies

basiliximab

Simulect

daclizumab

Zenapax

muromonab-CD3

Orthoclone OKT 3

Polyclonal Antibodies

antithymocyte globulin (lymphocyte immune globulin of equine or rabbit source)

Atgam (equine), Lymphoglobulin (rabbit)

Immunomodulators

anakinra

Kineret

glatiramer

Copaxone

interferon beta-1a

Avonex, Rebif

interferon beta-2b

Betaseron

leflunomide

Arava

Immunostimulating Antitumour Agents

BCG vaccine (intravesical)

ImmuCyst, OncoTICE, Pacis

melanoma theraccine

Melacine

Biologic Response Modifiers

Agents with Antitumour Activity

aldesleukin

Proleukin

interferon alfa-2a

Roferon-A

interferon alfa-2b

Intron A

peginterferon alfa-2a

Pegasys

peginterferon alfa-2b

Unitron-PEG

Agents Used to Treat Autoimmune Disease

etanercept

Enbrel

infliximab

Remicade

Monoclonal Antibodies

Antineoplastic Agents

rituximab

Rituxan

trastuzumab

Herceptin

Immunosuppressive Agents

adalimumab

Humira

basiliximab

Simulect

daclizumab

Zenapax

muromonab-CD3

Orthoclone OKT 3

Miscellaneous

abciximab

Reopro

digoxin immune FAB

Digibind

infliximab

Remicade

omalizumab

Xolair

palivizumab

Synagis

Drug Class

Generic Name

Trade Name

Other Agents

Hematopoietic Growth Factors

ancestim (SCF)

Stemgen

darbepoetin alfa

Aranesp

epoetin alfa

Eprex

filgrastim (G-CSF)

Neupogen

pegfilgrastim

Neulasta






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