Infectious Diseases  Drugs (Products approved for use in Canada) Drug Class Generic Name Trade Name ANTIBACTERIAL AGENTS Natural Penicillins penicillin G – oral, inj. Crystapen penicillin G benzathine – inj. Bicillin L-A** penicillin V – oral Pen-Vee Penicillinase-resistant (Antistaphyloccal) Penicillins cloxacillin – oral, inj. Extended-spectrum Penicillins (Aminopenicillins) amoxicillin – oral Amoxil ampicillin – oral, inj. Ampicin pivampicillin – oral Pondocillin pivmecillinam – oral Selexid Anti-Pseudomonal Penicillins piperacillin sodium – inj Pipracil Penicillin/Beta-lactamase Inhibitor Combinations amoxicillin/clavulanate – oral Clavulin piperacillin/tazobactam – inj. Tazocin ticarcillin/clavulanate – inj. Timentin First Generation Cephalosporins cefadroxil – oral Duricef cephalexin – oral cefazolin – inj. Second Generation Cephalosporins cefaclor – oral Ceclor cefotetan – inj. Cefotan cefoxitin – inj. cefprozil – oral Cefzil cefuroxime – inj. Zinacef cefuroxime axetil – oral Ceftin Third Generation Cephalosporins cefixime – oral Suprax cefotaxime – inj. Claforan ceftazidime – inj. Fortaz, Tazidime ceftizoxime – inj. Cefizox ceftriaxone – inj. Rocephin Fourth Generation Cephalosporins cefepime – inj. Maxipime ** Available only via Health Canada’s Special Access Program Drug Class Generic Name Trade Name ANTIBACTERIAL AGENTS Carbapenems ertapenem – inj. Ivanz imipenem/cilastatin – inj. Primaxin meropenem – inj. Merrem Aminoglycosides amikacin – inj. Amikin gentamicin – inj. Garamycin netilmicin – inj. Netromycin tobramycin – inj. , inhalation Nebcin, Tobi Macrolides and Ketolides azithromycin — oral, inj. Zithromax clarithromycin — oral Biaxin, Biaxin XL erythromycin — oral, inj. EES, Erybid, Eryc, Erythrocin, Erythromid, PCE telithromycin – oral Ketek Glycopeptides vancomycin – oral, inj. Vancocin Tetracyclines doxycycline – oral, inj.** Vibra-Tabs minocycline – oral Minocin tetracycline – oral Sulfonamide Combination Products sulfadiazine + trimethoprim (co-trimazine) – oral Coptin sulfamethoxazole + trimethoprim (cotrimoxazole) – oral, inj. Septra sulfisoxazole + erythromycin – oral Pediazole Fluoroquinolones ciprofloxacin – oral, inj. Cipro gatifloxacin – oral, inj. Tequin levofloxacin – oral, inj. Levaquin moxifloxacin – oral, inj. Avelox norfloxacin – oral ofloxacin – oral Floxin ** Available only via Health Canada’s Special Access Program Drug Class Generic Name Trade Name ANTIBACTERIAL AGENTS Various Antibiotics chloramphenicol – oral, inj. Chloromycetin clindamycin – oral, inj., vaginal cream Dalacin C fusidic acid – oral, inj., topical, ophthalmic Fucidin linezolid – oral, inj. Zyvoxam metronidazole – oral, inj., vaginal cream Flagyl quinupristin + dalfopristin – inj. Synercid Antimycobacterial Agents ethambutol – oral isoniazid – oral Isotamine para-aminosalicylate (PAS) – oral Nemasol sodium pyrazinamide – oral Tebrazid rifabutin – oral Mycobutin rifampin – oral Rifadin, Rofact isoniazid/pyrazinamide/ rifampin – oral Rifater Urinary Anti-infective fosfomycin Monurol methenamine HipRex, Mandelamine nalidixic acid NegGram nitrofurantoin MacroBID, Macrodantin trimethoprim trimethoprim/sulfadiazine (co-trimazine) Coptin Drug Class Generic Name Trade Name ANTIFUNGAL AGENTS Azole Antifungals Systemic fluconazole – oral, inj. Diflucan itraconazole – oral Sporanox ketoconazole – oral Nizoral voriconazole - oral, inj. Vfend Vaginal butoconazole – cream Gynazole clotrimazole – cream, inserts Canesten, Clotrimaderm econazole – cream, ovules Ecostatin miconazole – cream, ovules Micatin, Micozole, Monistat terconazole – cream, ovules Terazol Other Systemic Antifungal Agents amphotericin B – inj. Fungizone amphotericin B lipid complex-inj. Abelcet amphotericin B, liposomal – inj. AmBisome caspofungin – inj. Cancidas griseofulvin – oral Fulvicin terbinafine – oral Lamisil Antiprotozoals atovaquone – oral Mepron atovaquone + proguanil – oral Malarone chloroquine – oral Aralen mefloquine – oral Lariam metronidazole – oral, inj. Flagyl, Florazole ER paromomycin – oral Humatin pentamidine – inj. Pentacarinat primaquine – oral proguanil – oral Paludrine pyrimethamine – oral Daraprim Anthelmintics pyrantel pamoate Combantrin pyrvinium pamoate Vanquin Drug Class Generic Name Trade Name ANTIVIRAL AGENTS Nucleoside Antivirals acyclovir – oral, inj. Zovirax famciclovir – oral Famvir ganciclovir – oral, inj. Cytovene ganciclovir – ocular insert Vitrasert ribavirin – aerosol, inj.** Virazole ribavirin (oral) + interferon alfa-2b (inj.) Rebetron ribavirin (oral) + peginterferon alfa-2b (inj.) Pegetron valacyclovir – oral Valtrex valganciclovir – oral Valcyte Neuraminidase Inhibitors oseltamivir – oral Tamiflu zanamivir – inhaled Relenza Other Antivirals amantadine – oral Symmetrel (Antiviral) ANTIRETROVIRAL AGENTS Nucleoside Reverse Transcriptase Inhibitors (NRTIs) abacavir – oral Ziagen didanosine (ddI) – oral Videx lamivudine (3TC) – oral 3TC, Heptovir stavudine (d4T) – oral Zerit zalcitabine (ddC) – oral Hivid zidovudine (AZT) – oral, inj. Retrovir Combination NRTI Products lamivudine + zidovudine Combivir abacavir + lamivudine + zidovudine Trizivir Nucleotide Reverse Transcriptase Inhibitor tenofovir - oral Viread Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) delavirdine – oral Rescriptor efavirenz – oral Sustiva nevirapine – oral Viramune ** Available only via Health Canada’s Special Access Program Drug Class Generic Name Trade Name ANTIRETROVIRAL AGENTS Protease Inhibitors amprenavir — oral Agenerase atazanavir — oral Reyataz fosamprenavir — oral Telzir indinavir – oral Crixivan lopinavir + ritonavir – oral Kaletra nelfinavir – oral Viracept ritonavir – oral Norvir saquinavir – oral Fortovase saquinavir mesylate – oral Invirase Fusion Inhibitors enfuvirtide – inj. Fuzeon Biologic Response Modifiers interferon alfacon-1 Infergen interferon alfa-2a Roferon-A interferon alfa-2a Intron A Immune Globulins Non-specific immune globulins (IM) Baygam immune globulins (IV) Gamimune N, Iveegam Immuno, Gammagard S/D Specific cytomegalovirus Cytogam hepatitis B immune globulin Bayhep B rabies immune globulin BAYRAB; Imogam Rabies tetanus immune globulin BAYTET varicella zoster immune globulin Monoclonal Antibody against RSV (Respiratory Syncytial Virus) palivizumab Synagis Drug Class Generic Name Trade Name VACCINES* Viral Hepatitis hepatitis A vaccine Avaxim, Epaxal, Havrix, Vaqta hepatitis B vaccine Engerix-B, Recombivax HB hepatitis A & B vaccine Twinrix Influenza influenza virus vaccine (inactivated, split-virus) Fluzone, Fluviral S/F, Vaxigrip Meningococcal Disease meningococcal conjugate vaccine Menjugate, NeisVac-C Vaccine meningococcal polysaccharide vaccine Menomune, Mencevax AC Pneumococcal Infections pneumococcal conjugate vaccine Prevnar pneumococcal polysaccharide vaccine Pneumo 23, Pneumovax 23 Chicken Pox varicella virus vaccine Varivax, Varilrix MISCELLANEOUS Antithrombotic, Profibrinolytic, Anti-inflammatory Agent for Severe Sepsis drotrecogin alfa (activated Protein C) Xigris * List of vaccines excludes products used in routine primary immunization schedules during childhood and less commonly used products.
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